About Neuroinflammatory Disorders
Immune mediated neuroinflammation is a growing area of interest linking immune system activation with changes in brain function and behavior. Understanding these connections is essential for diagnosing and managing complex medical conditions.
Impacted Disorders and Illnesses
A wide range of conditions involve known or suspected immune-mediated neuroinflammation that results in neuropsychiatric symptoms. Understanding the clinical features, immune mechanisms, and psychiatric impact can transform how we approach care and research.
Neurodegenerative Disorder Alzheimer's Disease
A progressive neurodegenerative disorder that affects memory, cognition, behavior, and daily functioning.
Alzheimer’s disease research suggests it may reflect an infection-inflammation model in which immune dysregulation, pathogen exposure, and neuroinflammation contribute to cognitive decline, often accompanied by neuropsychiatric symptoms.
Inflammatory Bowel Disease Crohn's Disease
A chronic inflammatory bowel disease that can affect the digestive tract and contribute to systemic immune dysregulation.
Crohn’s disease is driven by complex interactions between pathogens, immunity, and neuroinflammation. Dysregulated gut–brain signaling may underlie both intestinal flares and systemic neuropsychiatric manifestations.
Autonomic Disorder POTS and Dysautonomia
Disorders of the autonomic nervous system that can affect heart rate, blood pressure, energy regulation, and cognitive function.
POTS and Dysautonomia can follow viral or bacterial infections. Immune activation, autoantibodies, and neuroinflammation may impair autonomic regulation, resulting in diverse cardiovascular and neuropsychiatric manifestations.
Post-Infectious Condition Long COVID
A post-infectious inflammatory condition that can occur after a SARS-CoV-2 infection.
Long COVID is a post-viral syndrome where persistent immune dysregulation and neuroinflammation drive fatigue, cognitive dysfunction, and neuropsychiatric symptoms.
Research Roadmap
Research is revealing a powerful connection between the immune system and brain function. Scientists are uncovering how immune responses can influence neurological health across a range of conditions — from neurodegenerative diseases to psychiatric disorders.
By unraveling the complex overlaps, researchers are laying the groundwork for more targeted, effective treatment strategies.
Discover how immune system responses can drive brain inflammation and contribute to complex neurological and psychiatric symptoms.
About FBSI
FBSI is a multidisciplinary organization dedicated to advancing the understanding of neuroinflammatory disorders and their impact on brain health. Through collaboration with leading experts, healthcare providers, and research institutions, we aim to bridge gaps in knowledge and improve patient outcomes.
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Latest News
Rethinking Psychiatric Symptoms: When Biology Drives Behavior
Emerging research continues to highlight the critical role of the immune system in brain health. Immune responses to infections and autoimmune triggers can lead to...
PANDAS Physicians Network Awards Grant to Support Biomarker Research in PANS
The Foundation for Brain Science and Immunology, through its division PANDAS Physicians Network (PPN), is pleased to announce a $25,000 grant awarded to Stanford Immune...
FBSI Launches Website Exploring the Intersection of Immunology, Infections, and Brain-Behavior Interactions
The Foundation for Brain Science and Immunology (FBSI) is proud to announce the launch of its newly designed website, www.brainimmunology.org, offering physicians and...
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